The devastating Nuclear Missile is the most prized weapon in the Terran arsenal. Constructed and stored at the Shadow Ops, and launched from this same building with the help of a Ghost, it releases a blast that little can withstand. Nukes are the fastest, if not easiest way of sanitizing large areas, may it be a battlefield or an enemy base. The sole counter for this weapon it seems lies within Protoss technology in the Mothership, the Time Bomb ability.

A Shadow Ops can have only one Nuclear Missile and one Drop at a time, but cannot contain two Nuclear Missiles or two Drop Pods at the same time.